Lionfish are well protected with their 18 venomous spines and therefor have few natural predators.
In their native range predators of lionfish include sharks, groupers, moray eels, frogfish, cornetfish and other scorpionfish.
Since lionfish are a new species in the Atlantic Ocean, the native fish have not evolved feeding on them. However, the following species are known to consume lionfish when presented with speared individuals:
PLEASE DON'T FEED THE LIONFISH!
Under no circumstance should speared lionfish be fed to marine life as it changes their natural behavior and they can become more aggressive.